Keap1/Nrf2 Pathway Regulates GFR by Increasing the Glomerular Effective Filtration Area Without Affecting the Afferent/Efferent Arteriole Ratio: Presentation at ERA-EDTA 2020

Pharmacologic and genetic investigation of the mechanisms of GFR regulation by Nrf2 using in vivo multiphoton microscope (MPM) imaging techniques.

Publication: Bardoxolone Methyl Decreases Megalin and Activates Nrf2 in the Kidney

A preclinical investigation on the role of megalin, a protein involved in the tubular reabsorption of albumin and lipid-bound proteins, in changes in albuminuria in animals treated with bardoxolone methyl.