PHOENIX was a Phase 2, open-label, multi-center, US-only trial of bardoxolone methyl in four separate cohorts of patients with autosomal dominant polycystic kidney disease, IgA nephropathy, type 1 diabetic chronic kidney disease, or focal segmental glomerulosclerosis. The trial enrolled 28 patients with type 1 diabetic chronic kidney disease and the primary endpoint was change in estimated glomerular filtration rate at Week 12.
Disclaimer
Bardoxolone methyl is an investigational drug. Safety and efficacy have not been established by any regulatory agency.